Overcoming the Challenges of Pulmonary RNA Delivery: Spray-Dried LNPs as Thermostable and Inhalable Therapeutics
- Presenting a next-generation inhalable RNA delivery platform based on spray-dried, room-temperature-stable LNP powders designed for efficient lung deposition upon pulmonary administration
- Detailing the formulation and process innovations that overcome key challenges such as RNA instability and inefficient delivery
- Highlighting therapeutic applications across chronic respiratory diseases such as severe asthma, COPD, and IPF