Transforming LNP Analytics: Label-free Insights at the Single-Particle Level
- SPARTA enables high-resolution, single-particle analysis of lipid nanoparticles (LNPs), revealing structural and compositional variability across batches to inform design, manufacturing, and targeting strategies
- By measuring abundance of lipid, peptide/protein, and drug components within each nanoparticle, SPARTA provides insights into payload distribution and heterogeneity
- Utilizing label-free, non-destructive Raman spectroscopy, SPARTA delivers detailed molecular fingerprints without altering or damaging the sample