Alexander Kros
Professor Leiden University
Alexander Kros is a Full Professor at Leiden University specializing in supramolecular and biomaterials chemistry, focusing on lipid nanoparticles, drug delivery, and cellular transport mechanisms. His research bridges chemistry and biology to advance targeted delivery systems and improve therapeutic efficacy
Seminars
Thursday 24th September 2026
Debate: Which Strategy Will Truly Break Liver Tropism & Enable Clinically Viable Extrahepatic Delivery
11:30 am
3–4 speakers each briefly defend a different approach in this open debate. The audience votes on the most promising strategy.
- Lipid chemistry vs formulation tuning vs hybrid systems
- Passive biodistribution control vs active targeting (ligands, peptides, etc.)
- Incremental optimisation vs completely new delivery paradigms
- What actually translates in vivo vs what only works in preclinical models
Thursday 24th September 2026
Achieving Cell-Specific LNP Delivery & BBB Penetration for Complex Diseases
9:30 am
- Explore strategies to modulate LNP composition and surface characteristics to enable selective targeting beyond hepatic tissues and improve cell-specific uptake
- Assess emerging approaches to overcome biological barriers, including the blood– brain barrier, to unlock delivery to previously inaccessible tissues
- Evaluate how advances in targeting, biodistribution control and in vivo performance are translating into more effective therapies for complex and hard-to-treat diseases
