Visualising & Engineering Intracellular LNP Behaviour: Unlocking Endosomal Escape & Cell-Specific Targeting

• Map intracellular LNP structure and integrity using advanced cryo-EM imaging
• Investigate endosomal escape mechanisms under physiologically relevant conditions
• Link nanoparticle morphology and phase behavior to cell-specific targeting outcomes
• Generate early in vitro and in vivo insights to inform rational LNP design beyond trial-and-error

Speakers:

Panagiota Papadopoulou

Marie Skłodowska- Curie Postdoctoral Fellow

National Hellenic Research Foundation