Visualising & Engineering Intracellular LNP Behaviour: Unlocking Endosomal Escape & Cell-Specific Targeting
- Map intracellular LNP structure and integrity using advanced cryo-EM imaging
- Investigate endosomal escape mechanisms under physiologically relevant conditions
- Link nanoparticle morphology and phase behavior to cell-specific targeting outcomes
- Generate early in vitro and in vivo insights to inform rational LNP design beyond trial-and-error